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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
37.58
Human Site:
S965
Identified Species:
63.59
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S965
T
K
F
I
V
K
D
S
V
E
E
N
M
L
K
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S965
T
K
F
I
V
K
D
S
V
E
E
N
M
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
S1062
T
K
F
I
V
K
D
S
V
E
E
N
M
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
S959
T
K
F
I
V
K
D
S
V
E
E
N
M
L
K
Rat
Rattus norvegicus
NP_001099948
974
110023
S930
T
K
F
I
V
K
D
S
V
E
E
N
M
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
K851
N
M
L
K
I
Q
N
K
K
R
E
L
A
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
S955
T
K
F
V
V
R
D
S
V
E
E
N
M
L
K
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
S900
T
K
F
I
V
K
D
S
V
E
E
N
M
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
T1021
Y
K
F
M
C
V
D
T
V
E
Q
R
I
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
S1044
T
K
F
L
V
R
D
S
V
E
E
A
M
L
E
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
Q766
E
E
R
I
L
E
M
Q
E
R
K
K
K
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
Q848
E
E
R
V
L
E
L
Q
Q
K
K
K
N
L
A
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L757
I
E
A
R
I
I
E
L
Q
E
K
K
A
N
M
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
S1180
Y
R
F
I
V
K
Q
S
V
E
M
R
M
L
R
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
86.6
93.3
N.A.
33.3
N.A.
N.A.
73.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
26.6
N.A.
100
100
N.A.
60
N.A.
N.A.
93.3
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
60
P-Site Similarity:
40
N.A.
N.A.
46.6
33.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
8
15
8
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
65
0
0
0
0
0
0
0
0
% D
% Glu:
15
22
0
0
0
15
8
0
8
79
65
0
0
0
8
% E
% Phe:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
58
15
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
65
0
8
0
50
0
8
8
8
22
22
8
8
50
% K
% Leu:
0
0
8
8
15
0
8
8
0
0
0
8
0
72
0
% L
% Met:
0
8
0
8
0
0
8
0
0
0
8
0
65
0
8
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
50
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
15
15
0
8
0
0
0
0
% Q
% Arg:
0
8
15
8
0
15
0
0
0
15
0
15
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% S
% Thr:
58
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
15
65
8
0
0
72
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _